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USE OF MANOMETRY FOR LARYNGEAL MASK AIRWAY REDUCES
> POSTOPERATIVE PHARYNGEAL ADVERSE EVENTS

>
> Anesthesiology 2010;112:652-7 Seet E, Yousaf F, Gupta S,
> Subramanyam R, Wong DT, Chung F

>
> Abstract
>
> Purpose The purpose of this study was to
> compare the difference in the incidence of pharyngolaryngeal
> complications in ambulatory surgical patients whose
> laryngeal mask airway (LMA) intracuff pressure was managed
> with manometry to limit inflation pressure to those who had
> routine cuff inflation without manometry.
>
> Background LMAs are routinely used for
> airway management. Serious complications are rare; however
> pharyngolaryngeal adverse events such as sore throat are
> common, with reported incidences as high as 42%. High
> intracuff pressures, > 60 cm H20 or 44 mm Hg have been
> associated with serious cranial nerve injuries secondary to
> LMA cuff over inflation. Unfortunately, routine monitoring
> of intracuff pressure with a manometer is not common
> practice.
>
> Methodology Ambulatory surgical patients,
> aged 18-60 years with ASA physical status I-III were
> recruited. Subjects were randomly assigned to routine care
> or pressure-limited to <60 cm H20 or 44 mm Hg. A
> standardized anesthetic technique was used for all patients.
> Anesthesia was induced with propofol and fentanyl and an LMA
> was inserted by an experienced clinician, followed by
> maintenance with desflurane and an air-oxygen mixture.
> Fentanyl was titrated as needed and patients were allowed to
> breathe spontaneously. Research assistants measured cuff
> pressure. Cuff pressure for subjects in the treatment group
> was kept < 60 cm H20 or 44 mm Hg. The incidence of sore
> throat, dysphagia, and dysphonia was evaluated by a blinded
> research assistant at 1, 2 and 24 hours postoperatively. The
> primary outcome of composite pharyngolaryngeal complications
> (sore throat + dysphagia + dysphonia) was compared between
> the two groups using a chi square test. Logistic regression
> was used to asses risk factors associated with
> pharyngolaryngeal complications.
>
> Result A total of 203 subjects completed
> the study (pressure limited group n = 97, routine care group
> n = 103). No differences in baseline demographics or
> perioperative data were found between groups. Immediately
> after LMA insertion, cuff pressure averaged 112 ± 59 mm Hg
> in the pressure-limited group compared to 114 ± 57 mm Hg in
> the routine care group. After adjustment of intracuff
> pressure in the pressure-limited group, cuff pressure was
> significantly lower than the control group (40 ± 6 vs. 114
> ± 57 mm Hg, P < 0.001). Composite pharyngolaryngeal
> adverse events were significantly less frequent in the
> pressure-limited group (13.4% vs. 45.6%, P < 0.001). Use
> of manometry decreased the relative risk of complications by
> 70.6% with a number needed to treat of 3 (95% CI 2.2- 7.5)
> needed to prevent complications with the pressure-limited
> group. The incidence of sore throat was significantly less
> at 2 hours (2.1% vs. 8.7%, P <0.05) and 24 hours (3.1%
> vs. 13.6%, P < 0.05) in the pressure-limited group.
> Dysphagia was significantly less at all three time points (1
> h: 1% vs. 12.6%; 2 h: 0% vs. 12.6%; 24 h: 2.1% vs. 8.7%, P
> < 0.05), whereas dysphonia was only significantly less at
> 1 hour (5.2% vs. 15.5%, P < 0.05). Logistic regression
> revealed that the only variable predictive of
> pharyngolaryngeal complications was intracuff pressure (P =
> 0.0001). Clinical experience, number of insertion attempts,
> ease of insertion, blood on LMA, duration of surgery, use of
> an oral airway, incidence of larygospasm, and suctioning
> were not associated with complications.
>
> Conclusion Use of a manometer to keep LMA
> intracuff pressure < 60 cm H20 or 44 mm Hg significantly
> decreased the incidence of sore throat, dysphagia and
> dysphonia in ambulatory surgical patients allowed to
> spontaneously breathe under general anesthesia with
> desflurane and air-oxygen mixture. The authors recommended
> the routine use of a pressure manometer to keep LMA
> intracuff pressures < 60 cm H20 or 44 mm Hg.
>
> Comment
>
> This was a well designed prospective, randomized trial
> which provides compelling evidence for keeping LMA intracuff
> pressures < 60 cm H20 or 44 mm Hg to limit the incidence
> of pharyngolaryngeal complications. I was amazed at how LMA
> intracuff pressures in both groups after placement were
> almost two times the manufactures’ recommendation for
> intracuff pressure (< 60 cm H20 or 44 mm Hg). In this day
> of increasing ambulatory surgery I think it is important
> that we continue to find ways to decrease complications and
> improve outcomes. I don’t think we will ever find a way to
> completely eliminate the incidence of sore throat after use
> of an LMA (or intubation); however anything we can do
> certainly may help. After reading this study I began using a
> manometer routinely with LMAs and found that my intracuff
> pressures were still higher than what is recommended, so I
> now use the manometer to keep the pressure less than 60 cm
> H20 or 44 mm Hg. Likewise, I teach my students to routinely
> use a manometer and to keep cuff pressures below recommended
> maximum pressure.
>
> Dennis Spence, PhD, CRNA
>
> The views expressed in this article are those of the author
> and do not reflect official policy or position of the
> Department of the Navy, Department of Defense or the United
> States Government.
>
> © Copyright 2010 Anesthesia Abstracts · Volume 4 Number
> 3, March 28, 2010
>
> ...................................................................................................................................................................................................................................
> Charlene Burk
> Administrative Assistant
> Lifelong Learning, LLC
> charlie@lifelonglearningllc.com
>
>
>
> www.LifelongLearningLLC.com